Progressive multifocal leukoencephalopathy restricted to the posterior fossa in a patient with systemic lupus erythematosus
AUTOR(ES)
Gonçalves, Fabrício Guimarães, Lamb, Leslie, Del Carpio-O'Donovan, Raquel
FONTE
Brazilian Journal of Infectious Diseases
DATA DE PUBLICAÇÃO
2011-12
RESUMO
Progressive multifocal leukoencephalopathy is a neurological infectious disease caused by the John Cunningham polyomavirus (JCV), an opportunistic agent with worldwide distribution. This disease is frequently seen in immunosuppresed patients and rarely associated with systemic lupus erythematosus. In the central nervous system PML demyelinating lesions occur in the supratentorial compartment. The authors describe a rare case of PML secondary to SLE treatment with atypical presentation restricted to the posterior fossa.
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