Profound effect of normalization on detection of differentially expressed genes in oligonucleotide microarray data analysis
AUTOR(ES)
Hoffmann, Reinhard
FONTE
BioMed Central
RESUMO
A number of procedures for normalization and detection of differentially expressed genes have been proposed. Four different normalization methods and all possible combinations with three different statistical algorithms have been used for detection of differentially expressed genes on a dataset. The number of genes detected as differentially expressed differs by a factor of about three.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=126238Documentos Relacionados
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