Production of Peptide Ergot Alkaloids in Submerged Culture by Three Isolates of Claviceps purpurea

AUTOR(ES)

Amici, A. M.

RESUMO

Three strains of Claviceps purpurea (Fr.) Tul., isolated from sclerotia grown on rye, produce under submerged conditions ergocryptine and ergotamine, ergocornine and ergosine, and ergocristine, respectively. All of the strains either lacked the ability to produce conidia or formed them sparingly, but they accumulated large quantities of lipids and sterols. The fermentations are typically divided into two phases. The first is characterized by the rapid utilization and exhaustion of the phosphate contained in the medium, rapid uptake of ammonium nitrogen and of citric acid, rapid growth, and low alkaloid production; the second phase is characterized by slower growth and by a marked accumulation of lipids, sterols, and alkaloids.

Documentos Relacionados

• Ergotamine Production in Submerged Culture and Physiology of Claviceps purpurea
• Long-Term Production of Ergot Peptides by Immobilized Claviceps purpurea in Semicontinuous and Continuous Culture
• Extracellular metabolism of sucrose in a submerged culture of Claviceps purpurea: formation of monosaccharides and clavine alkaloids.
• GLUTAMIC DECARBOXYLASE OF ERGOT, CLAVICEPS PURPUREA
• Role of Glycols and Tweens in the Production of Ergot Alkaloids by Claviceps paspali