Prevalence of CagA and VacA Antibodies in Children with Helicobacter pylori-Associated Peptic Ulcer Compared to Prevalence in Pediatric Patients with Active or Nonactive Chronic Gastritis

AUTOR(ES)

Alarcón, T.

FONTE

American Society for Microbiology

RESUMO

VacA and CagA serological responses were detected in pediatric patients: 44 and 56%, respectively, in peptic ulcer (PU) patients, 33.3 and 44.4% in active chronic gastritis (ACG) patients, and 23.2 and 39.2% in non-ACG patients. Higher seroprevalence to CagA+VacA and to CagA+VacA+35-kDa antigen was found among PU patients. However, a low level of sensitivity and specificity was found for indirect detection of PU patients.

Documentos Relacionados

• Prevalence of cagA and vacA genes in isolates from patients with Helicobacter pylori-associated gastroduodenal diseases in Recife, Pernambuco, Brazil
• Helicobacter pylori‐associated peptic ulcer and florid follicular gastritis mimicking a malignancy
• Helicobacter pylori cagA Status and s and m Alleles of vacA in Isolates from Individuals with a Variety of H. pylori-Associated Gastric Diseases
• CagA Antibodies in Japanese Children with Nodular Gastritis or Peptic Ulcer Disease
• Prevalence of Helicobacter pylori vacA and cagA Genotypes in Ethiopian Dyspeptic Patients