Prenatal diagnosis of a de novo non-fluorescent Y chromosome.
AUTOR(ES)
Priest, J H
RESUMO
We report a case with non-mosaic Yq-, missing the fluorescent segment, and detected as a fetus studied for advanced maternal age. The father had a Y chromosome of average size and paternity was established wih a plausibility of 97.7% by HLA and erythrocyte antigen typing. The child had a normal male antigen typing. The child had a normal male phenotype at delivery and developmental milestones were normal through the first year of life. The Yq- showed no mitotic instability since it was retained in foreskin culture for its in vitro lifetime of 60 population doublings.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1048578Documentos Relacionados
- Characterisation of a satellited non-fluorescent Y chromosome (Y[nfqs]) by FISH.
- Racial variation of a non-fluorescent segment of the Y chromosome in East Indians.
- Length heteromorphisms of fluorescent (f) and non-fluorescent (nf) segments of human Y chromosome: classification, frequencies, and incidence in normal Caucasians.
- Interconversion of Anthozoa GFP-like fluorescent and non-fluorescent proteins by mutagenesis
- Human chromosomal heteromorphisms in American blacks. VI. Higher incidence of longer Y owing to non-fluorescent (nf) segment.