Prediction of protein folding rates from the amino acid sequence-predicted secondary structure

AUTOR(ES)

Ivankov, Dmitry N.

FONTE

National Academy of Sciences

RESUMO

We present a method for predicting folding rates of proteins from their amino acid sequences only, or rather, from their chain lengths and their helicity predicted from their sequences. The method achieves 82% correlation with experiment over all 64 “two-state” and “multistate” proteins (including two artificial peptides) studied up to now.

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