Polymer-based surface plasmon resonance biochip: construction and experimental aspects

AUTOR(ES)

Moreira, Cleumar da Silva, Oliveira, Leiva Casemiro, Fischer, Robert, Medeiros, Eliton Souto, Lima, Antonio Marcus Nogueira, Neff, Helmut

FONTE

Res. Biomed. Eng.

DATA DE PUBLICAÇÃO

04/03/2016

RESUMO

Abstract Introduction: Surface plasmon resonance biosensors are high sensitive analytical instruments that normally employ glass materials at the optical substrate layer. However, the use of polymer-based substrates is increasing in the last years due to favorable features, like: disposability, ease to construction and low-cost design. Review Recently, a polymer-based SPR biochip was proposed by using monochromatic and polychromatic input sources. Its construction and experimental considerations are detailed here. Experimental considerations and results, aspects from performance characteristics (resonance parameters, sensitivity and full width at half maximum – FWHM – calculations) are presented for hydrophilic and hydrophobic solutions. It is included also a brief description of the state of the art of polymer-based SPR biosensors.

Documentos Relacionados

• Making sense of polymer-based biosensors
• A chemically diverse conducting polymer-based "electronic nose".
• Polymer-Based Sustained-Release Dosage Forms for Protein Drugs, Challenges, and Recent Advances
• Polymer-based gene delivery with low cytotoxicity by a unique balance of side-chain termini
• Polymer-Based Enzyme-Linked Immunosorbent Assay Using Human Papillomavirus Type 16 (HPV16) Virus-Like Particles Detects HPV16 Clade-Specific Serologic Responses