Polycarpol in Unonopsis, Bocageopsis and Onychopetalum Amazonian species: chemosystematical implications and antimicrobial evaluation

AUTOR(ES)

Silva, Felipe M.A. da, Lima, Bruna R. de, Soares, Elzalina R., Almeida, Richardson A. de, Silva Filho, Francinaldo A. da, Corrêa, Wallace R., Salvador, Marcos J., Souza, Antonia Q.L. de, Koolen, Hector H.F., Souza, Afonso D.L. de, Pinheiro, Maria L.B.

FONTE

Rev. bras. farmacogn.

DATA DE PUBLICAÇÃO

2015-02

RESUMO

Polycarpol, a recurrent lanostane-type triterpene in Annonaceae family, was confirmed by thin layer chromatography and mass spectrometry analysis in the aerial parts (twigs and trunk barks) of Unonopsis duckei R.E. Fr., U. floribunda Diels, U. rufescens (Baill.) R.E. Fr., U. stipitata Diels, Onychopetalum amazonicum R.E. Fr. and Bocageopsis pleiosperma Maas. Its chemotaxonomic significance was discussed for these three genera, as well for the Annonaceae family. In addition, the antimicrobial activity against several strains of microorganisms was evaluated for the first time for this compound, being observed significant antibacterial activity against Staphylococcus aureus (ATCC 6538), Staphylococcus epidermidis (ATCC 1228) and Escherichia coli (ATCC 10538 and ATCC 10799) with minimal inhibitory concentration values between 25 and 50 μg ml−1.

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