Poly(A)-binding proteins: multifunctional scaffolds for the post-transcriptional control of gene expression
AUTOR(ES)
Mangus, David A
FONTE
BioMed Central
RESUMO
The poly(A)-binding proteins (PABPs) are highly conserved polypeptides that bind to poly(A) tails of mRNAs. Although they lack catalytic activity, PABPs have several roles, including actions in regulating the length of the poly(A) tail, in regulating the export of mRNAs from the nucleus, in translation initiation and termination, in recycling of ribosomes, and in mRNA stability.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=193625Documentos Relacionados
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