Plasma Progesterone and 17-hydroxyprogesterone in normal men and children with congenital adrenal hyperplasia

AUTOR(ES)

Strott, Charles A.

RESUMO

Plasma 17-hydroxyprogesterone (17-OHP) concentrations in normal men averaged 0.094 μg/100 ml. Studies using suppressive doses of androgens and glucocorticoids showed that 90% of the 17-OHP originated from the Leydig cell. The 17-OHP production rate was 1.8 mg/24 hr. Plasma 17-OHP has a marked circadian variation, the 8 p.m. values being only 40% of the 8 a.m. values. Plasma luteinizing hormone measured in the same samples did not vary.

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