Piracy of adhesins: attachment of superinfecting pathogens to respiratory cilia by secreted adhesins of Bordetella pertussis.
AUTOR(ES)
Tuomanen, E
RESUMO
Two proteins secreted by Bordetella pertussis are known to mediate adherence of these bacteria to mammalian respiratory cilia. When either ciliated cells or other pathogenic bacteria were pretreated with these adhesins, Streptococcus pneumoniae, Haemophilus influenzae, and Staphylococcus aureus acquired the ability to adhere to cilia in vitro and in vivo. Such piracy of adhesins may contribute to superinfection in mucosal diseases such as whooping cough.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=260259Documentos Relacionados
- Development of a rat model for respiratory infection with Bordetella pertussis.
- Crystallization of pertussigen from Bordetella pertussis.
- Extracytoplasmic adenylate cyclase of Bordetella pertussis.
- Characterization of environmental regulators of Bordetella pertussis.
- Invasion of HeLa 229 cells by virulent Bordetella pertussis.
