Phytochemical investigation of Wissadula periplocifolia (L.) C. Presl and evaluation of its antibacterial activity

Teles, Yanna C. F., Gomes, Roosevelt A., Oliveira, Micaelly da S., Lucena, Kaio L. de, Nascimento, José S. do, Agra, Maria de Fátima, Igoli, John O., Gray, Alexander I., Souza, Maria de Fátima V. de

Phytochemical investigation of Wissadula periplocifolia (L.) C. Presl and evaluation of its antibacterial activity

AUTOR(ES)

Teles, Yanna C. F., Gomes, Roosevelt A., Oliveira, Micaelly da S., Lucena, Kaio L. de, Nascimento, José S. do, Agra, Maria de Fátima, Igoli, John O., Gray, Alexander I., Souza, Maria de Fátima V. de

FONTE

Quím. Nova

DATA DE PUBLICAÇÃO

2014

RESUMO

A phytochemical study on the aerial parts of Wissadula periplocifolia using chromatographic techniques has led to the isolation of sitosterol (1a), stigmasterol (1b), sitosterol 3-O-β-D-glucopyranoside (2a), stigmasterol 3-O-β-D-glucopyranoside (2b), phaeophytin A (3), 13²-hydroxy-(13²-S)-phaeophytin A (4), phaeophytin B (5), 17³-ethoxyphaeophorbide (6), 3,4-seco-urs-4(23),20(30)-dien-3-oic acid (7), 3-oxo-21β-H-hop-22(29)-ene (8), dammaradienone (9a), and taraxastenone (9b). The isolated compounds were characterised by spectroscopic analysis. A preliminary assay to evaluate the antibacterial activity of W. periplocifolia extracts and fractions showed that the dichloromethane, ethyl acetate, and n-butanol fractions were active against Enterococcus faecalis.