Phytochemical Analysis, Multi-Element Composition and Biological Activities of Extracts and Lupenone from Albizia inundata (Mart.) Barneby & J.W.Grimes

Andrade, Eberson M. J.; Teixeira, Jéssica S.; Silva, Dahara K. C.; Santos, Tatiana B. dos; Korn, Maria G. A.; Brandão, Hugo N.; Ferraz, Caline G.; Meira, Cássio S.; Soares, Milena B. P.; Guimarães, Elisava T.; C. S. Neta, Lourdes; F. S. Júnior, Aníbal

Phytochemical Analysis, Multi-Element Composition and Biological Activities of Extracts and Lupenone from Albizia inundata (Mart.) Barneby & J.W.Grimes

AUTOR(ES)

Andrade, Eberson M. J.; Teixeira, Jéssica S.; Silva, Dahara K. C.; Santos, Tatiana B. dos; Korn, Maria G. A.; Brandão, Hugo N.; Ferraz, Caline G.; Meira, Cássio S.; Soares, Milena B. P.; Guimarães, Elisava T.; C. S. Neta, Lourdes; F. S. Júnior, Aníbal

FONTE

J. Braz. Chem. Soc.

DATA DE PUBLICAÇÃO

2020-09

RESUMO

In this study, antimicrobial activity of extracts and lupenone from A. inundata (Fabaceae, Mimosoideae), were tested. In addition, the multi-element composition of the leaves, bark and stems (heartwood) of A. inundata was evaluated using inductively coupled plasma optical emission spectrometry (ICP OES). Lupenone was isolated in the petroleum ether extract of leaves, for the first time. Biological assays were conducted to evaluate the antimicrobial (antibacterial, antifungal and antiparasitic) of extracts, their fractions and lupenone. The results showed antimicrobial and antileishmanial activity of these compounds, which may be useful for obtaining a chemical composition and biological activity database on Albizia species. For multi-element composition, we found the mean concentrations (minimum-maximum) of Al, Ca, Cr, Cu, Fe, K, Mg, Mn, Ni, P, V and Zn in the samples ranged between 0.06 and 265.41 µg g-1. Concentration ranges of Cu, Fe, Mn and Zn are large, which makes these samples as additional sources of these macronutrients.