Pharmacokinetics of a single dose of rimantadine in young adults and children.
AUTOR(ES)
Anderson, E L
RESUMO
Single doses of rimantadine were given to children and young adults to evaluate the safety and pharmacokinetics of this antiviral compound. The half-life of rimantadine in young adults was 27.7 +/- 4.9 h for tablets and 27.8 +/- 8.0 h for syrup preparations. A total of 10 children, 5 to 8 years old, received a syrup preparation of rimantadine. The half-life of rimantadine in children was 24.8 +/- 9.4 h. A single dose of rimantadine was well tolerated in young adults and children.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=174886Documentos Relacionados
- Single-dose pharmacokinetics of ceftriaxone in infants and young children.
- Comparative Single-Dose Pharmacokinetics of Amantadine Hydrochloride and Rimantadine Hydrochloride in Young and Elderly Adults
- Comparative single-dose pharmacokinetics of amantadine hydrochloride and rimantadine hydrochloride in young and elderly adults
- Single-dose pharmacokinetics of piperacillin and tazobactam in infants and children.
- Multiple-dose pharmacokinetics of rimantadine in elderly adults.
