Persistence of chlamydial antibodies after pelvic inflammatory disease.
AUTOR(ES)
Puolakkainen, M
RESUMO
The persistence of chlamydial immunoglobulin G (IgG) antibodies and long-term sequelae of pelvic inflammatory disease (PID) were studied in 70 women who had been treated for PID 3 to 6 years previously. Fifty-one women had had PID associated with Chlamydia trachomatis infection (Chlamydia group), and 19 women had had PID not associated with C. trachomatis (non-Chlamydia group). Chlamydial IgG antibodies, as determined by the indirect immunofluorescence test with inclusions of C. trachomatis L2 as antigens, persisted at stable levels in 43% of the women for up to 6 years; 43% of the women showed a decrease in IgG titer, and 13% showed an increase. IgA antibody levels in serum correlated with IgG antibody levels in serum and with the presence of cervical IgA antibodies. Both serum antibodies and cervical IgA antibodies were more often found in the Chlamydia group. Forty-two percent of the women were infertile. Every fifth subsequent pregnancy was ectopic. The presence of cervical IgA antibodies might protect the women from tubal damage.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=268751Documentos Relacionados
- Antichlamydial antibodies in pelvic inflammatory disease.
- Chlamydial pelvic infection in cats: a model for the study of human pelvic inflammatory disease.
- Pathogenesis of pelvic inflammatory disease.
- Morbidity associated with pelvic inflammatory disease.
- Beta-lactam susceptibility of Neisseria gonorrhoeae isolates from pelvic inflammatory disease.
