Perfil de sensibilidade da Pseudomonas aeruginosa â estudo retrospectivo em dois hospitais do Recife â PE

AUTOR(ES)
DATA DE PUBLICAÇÃO

2006

RESUMO

An increasing frequency of multiresistant bacteria profile to antibiotics has grown in the last few years. Between gram-negative bacterias, the Pseudomonas aeruginosa (P.aeruginosa) shows a great facility to development mechanisms of multidrug-resistance. The objective of this study was to identify the susceptibility patterns to several antibiotics classes against gramnegative bacterias and to compare analysis between intensive care units(UCI) and the wards of two tertiary Hospitals in Recife/PE. The study was carried out between September 2004 - January 2006.The antimicrobial susceptibility testing was performed by the disc diffusion method according to NCCLS (National Commitee for Clinical and Laborastory Standards) guidelines. The following antibiotics were tested, and their respective susceptibility are desc ribed: polimixina (88,7%); piperacillin-tazobactam (66,2%); aztreonam (59,8%); amikacin (59,4%); meropenem (58,2%); imipenem (57,7%); ciprofloxacin (49,7%); gentamicin e cefepime (48,6%); ceftazdime (30,05) e cefotaxime (6,8%). The highest portion of pseudomonas isolated was from urinary samples(26,7%) followed by respiratory tract samples(26,1%). Differences in the antibiotic profile was found between the ICU and others wards with a statistically significant difference (p<0,05)in one of the hospitals studied. In conclusion, the frequency of P. aeruginosa multidrug-resistant was higher in this two hospitals in Recife than others hospitals in Brazil and abroad.This higher frequency was observed to be mainly in patients in the ICU. Close epimiologic monitoring e optimization of antibiotics protocols will be urgent necessary in a way to reduce the clone dissemination

ASSUNTO(S)

multi-resistÃncia ciÃncias da saÃde pseudomonas aeruginosa recife multidrug-resistant recife pseudomonas aeruginosa epidemiologia susceptibility

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