Penicillin-Induced Lysis of Escherichia coli in Medium That Does Not Support Sustained Growth

AUTOR(ES)
RESUMO

Exponentially growing cells of an Escherichia coli auxotroph that are washed and resuspended in buffer containing a carbon source undergo sufficient growth to render them susceptible to penicillin-induced lysis, even in the absence of the required metabolite. This lysis is probably responsible for the reduction in intracellular enzyme activity previously attributed to a direct effect of penicillin upon the enzyme.

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