On the translocation of proteins across membranes.
AUTOR(ES)
Singer, S J
RESUMO
Many proteins of intracellular organelles are first synthesized in the cytoplasm and are then specifically transferred across the membranes of the organelles. On the assumption that these transfers all occur by the same basic mechanism, we enumerate the rather stringent requirements that the mechanism must satisfy. A unitary molecular mechanism is then proposed that meets these requirements.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=304352Documentos Relacionados
- Disulfide bonds and the translocation of proteins across membranes.
- Translocation of DNA across bacterial membranes.
- Particle uptake and translocation across epithelial membranes.
- Tryptic dissection and reconstitution of translocation activity for nascent presecretory proteins across microsomal membranes.
- Posttranslational translocation of influenza virus hemagglutinin across microsomal membranes.
