Occult hepatitis B virus infection among injecting drug users in the Central-West Region of Brazil
AUTOR(ES)
Matos, Marcia Alves Dias de, Ferreira, Renata Carneiro, Rodrigues, Fabiana Perez, Marinho, Tamiris Augusto, Lopes, Carmen Luci Rodrigues, Novais, Antonia Carlos Magalhaes, Motta-Castro, Ana Rita Coimbra, Teles, Sheila Araujo, Souto, Francisco Jose Dutra, Martins, Regina Maria Bringel
FONTE
Mem. Inst. Oswaldo Cruz
DATA DE PUBLICAÇÃO
2013-05
RESUMO
The prevalence of occult hepatitis B virus (HBV) infection was investigated in 149 hepatitis B surface antigen (HBsAg) negative injecting drug users (IDUs) in the Central-West Region of Brazil. Of these individuals, 19 were positive for HBV DNA, resulting in an occult HBV infection prevalence of 12.7% (19/149); six of these 19 individuals had anti-HBV core and/or anti-HBV surface antibodies and 13 were negative for HBV markers. All IDUs with occult hepatitis B reported sexual and/or parenteral risk behaviours. All HBV DNA-positive samples were successfully genotyped. Genotype D was the most common (17/19), followed by genotype A (2/19). These findings reveal a high prevalence of occult HBV infection and the predominance of genotype D among IDUs in Brazil's Central-West Region.
Documentos Relacionados
- Prevalence of hepatitis C virus infection among recyclable waste collectors in Central-West Brazil
- Decrease in hepatitis B prevalence among blood donors in Central-West Brazil
- Pertussis in the central-west region of Brazil: one decade study
- Active and latent tuberculosis in prisoners in the Central-West Region of Brazil
- Epidemiology of hepatitis C virus infection among injecting drug users in Australia.