Observations on intravenous administration of lignocaine in patients with myocardial infarction.
AUTOR(ES)
Campbell, N P
RESUMO
Lignocaine was administered intravenously to 36 patients with acute myocardial infarction. A bolus of 100 mg followed by an infusion of 2 mg/minute failed to maintain plasma levels above 2 microgram/ml. A bolus of 100 mg followed by 4 mg/minute also failed to maintain satisfactory plasma concentrations during the first hour of therapy. A bolus of 75 mg was combined with an infusion of 10 mg/minute for 20 minutes followed by 1.5 mg/minute. Satisfactory plasma concentrations during the first hour were observed in 94 per cent of the estimations. No important adverse side effects occurred during the infusion of 10 mg/minute.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=483581Documentos Relacionados
- Lignocaine: effects on coronary blood flow in patients with recent myocardial infarction.
- Blood levels of lignocaine after intramuscular administration to patients with proven or suspected acute myocardial infarction.
- Lignocaine therapy in myocardial infarction.
- Some observations on haematocrit changes in patients with acute myocardial infarction.
- Comparison between effectiveness of intramuscular and intravenous lignocaine on ventricular arrhythmia complicating acute myocardial infarction.