Nucleotide sequence of the gene encoding the serotype-specific glycoprotein of UK bovine rotavirus.
AUTOR(ES)
Elleman, T C
RESUMO
The nucleotide sequence of the gene which encodes the major outer-shell glycoprotein of UK bovine rotavirus has been determined. The dsRNA genome segment encoding this protein was converted into ds cDNA and cloned into pBR322 for sequence studies. The gene is 1062 base pairs in length and contains a single, long, open reading-frame capable of coding for a protein of 326 amino-acids. This would leave 5' and 3' non-coding regions of 48 and 36 nucleotides in the mRNA. The predicted amino-acid sequence contains three possible glycosylation sites of the type Asn-X-Ser Thr, and an extremely hydrophobic N-terminal region. This sequence is discussed in the light of the known properties and functions of the protein.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=326079Documentos Relacionados
- Serotype-specific glycoprotein of simian 11 rotavirus: coding assignment and gene sequence.
- Nucleotide sequence of the gene encoding the serotype-specific antigen of human (Wa) rotavirus: comparison with the homologous genes from simian SA11 and UK bovine rotaviruses.
- Prevalent patterns of serotype-specific seroconversion in Mexican children infected with rotavirus.
- Sequence homology between human and animal rotavirus serotype-specific glycoproteins.
- Gene sequence of the VP7 serotype specific glycoprotein of Gottfried porcine rotavirus.