Nucleotide sequence of the gene encoding the matrix protein of Newcastle disease virus.

AUTOR(ES)

Chambers, P

RESUMO

The nucleotide sequence of the gene encoding the matrix (M) protein of the Beaudette C strain of Newcastle disease virus (NDV) has been determined from overlapping cDNA clones. Control sequences typical of paramyxovirus mRNA start and polyadenylation signals have been identified. Assuming that the M gene starts and finishes at these sequences, the M gene is 1241 nucleotides long and encodes one long open reading frame of 364 amino acids, corresponding to a polypeptide of molecular weight 39605, in good agreement with estimates from SDS gels. The M protein has an amino acid sequence that is both hydrophobic and highly basic. The NDV M protein has sequence homologies to the M proteins of Sendai, measles, canine distemper and respiratory syncytial viruses.

Documentos Relacionados

• Nucleotide sequence of the gene encoding respiratory syncytial virus matrix protein.
• Nucleotide sequence of the phosphoprotein (P) gene of Newcastle disease virus (strain Beaudette C).
• Nucleotide sequence of the human parainfluenza virus 3 matrix protein gene.
• Nucleotide sequence of the gene encoding the fusion (F) glycoprotein of human respiratory syncytial virus.
• Nucleotide sequence of the gene for the major structural protein of SV40 virus.