Niveis plasmaticos de vasopressina em cirugia de correção de aneurisma de aorta abdominal / Plasmatic levels of vasopressin in the4 corrective surgery of abdominal aorta aneurysm
AUTOR(ES)
Adriana Camargo Carvalho
FONTE
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia
DATA DE PUBLICAÇÃO
16/07/2009
RESUMO
Objectives: To evaluate plasma vasopressin (AVP) levels in patients undergoing uncomplicated conventional abdominal aortic aneurysm (AAA) repair. Design: Prospective, descriptive, observational study. Interventions: None. Setting: A tertiary academic hospital at Campinas, Sao Paulo, Brazil. Methods: Plasma AVP concentrations were measured by radioimmunoassay in 22 nonconsecutive adult patients undergoing infra-renal AAA repair under combined general and epidural anesthesia at the following moments: pre-operative (T0); 2h (T1) and 6h (T2) after surgical procedure; and by the morning at the 1st (T3), 2nd (T4) and 3rd (T5) postoperative days. Some clinical and laboratory variables were concomitantly recorded. Results: Patients mean age was 68.2±10.2 years (ranging 49-82 years), with 17 males and 05 females. AVP plasma levels (mean±SD pg/mL) were low and within the normal range at T0 (1.4±0.7; control), showing a significant increase at T1 (62.6±62.9; p<0.001) and at T2 (31.5±49.7; p<0.001), with a marked progressive fall in the subsequent days, returning to basal levels at T5 (2.1±3.8; p = NS). Positive and statistically significant correlations were found between AVP levels and glycemia, lactatemia and white blood cells counts, but not with systemic arterial pressure or plasma osmolarity during postoperative period. Conclusions: The pattern of plasma AVP increasing, peaking during the 1st postoperative hours, suggests that this response is directly related to the surgical trauma, but not to hemodynamic and/or plasmatic osmolarity derangements. The pathophysiology of this pattern of stress response is still unclear, and deserves further investigation in general surgical procedures
ASSUNTO(S)
cirurgia aneurisma da aorta abdominal estresse vasopressina surgery abdominal aortic aneurysm stress vasopressin
ACESSO AO ARTIGO
http://libdigi.unicamp.br/document/?code=000449768Documentos Relacionados
- Vasopressina plasmática em pacientes submetidos à correção de aneurisma de aorta infrarrenal
- Correção de aneurisma de aorta abdominal em paciente com dois rins pélvicos
- Correção endovascular de aneurisma de aorta abdominal em complicação tardia de dissecção de aorta tipo A
- Hérnias incisionais no pós-operatório de correção de aneurisma de aorta abdominal
- Correção endovascular de aneurisma de aorta abdominal pararrenal pela técnica da chaminé