NEW EMBO MEMBER’S REVIEW: Lysosomal cysteine proteases: facts and opportunities

AUTOR(ES)

Turk, Vito

FONTE

Oxford University Press

RESUMO

From their discovery in the first half of the 20th century, lysosomal cysteine proteases have come a long way: from being the enzymes non-selectively degrading proteins in lysosomes to being those responsible for a number of important cellular processes. Some of the features and roles of their structures, specificity, regulation and physiology are discussed.

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