Neutralization of Chlamydia trachomatis cell culture infection by serovar-specific monoclonal antibodies.

AUTOR(ES)

Lucero, M E

RESUMO

Seventeen monoclonal antibodies (MAs) were tested. Five of seven serovar-specific MAs from five different serovars and two of five subspecies-specific MAs showed neutralizing activity as well as serovar specificity. No species- or genus-specific MAs showed neutralizing activity. No neutralization occurred without complement. Results indicate neutralization was serovar specific and complement dependent.

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