Needle-Free Skin Patch Vaccination Method for Anthrax

AUTOR(ES)

Matyas, Gary R.

FONTE

American Society for Microbiology

RESUMO

Three immunizations of mice with recombinant protective antigen (rPA) by transcutaneous immunization (TCI) induced long-term neutralizing antibody titers that were superior to those obtained with aluminum-adsorbed rPA. In addition, rPA alone exhibited adjuvant activity for TCI. Forty-six weeks after completion of TCI, 100% protection was observed against lethal anthrax challenge.

Documentos Relacionados

• Protection against Tetanus by Needle-Free Inoculation of Adenovirus-Vectored Nasal and Epicutaneous Vaccines
• US judge halts compulsory anthrax vaccination for soldiers
• Cost effectiveness of the Oregon quitline “free patch initiative”
• Vaccination against Anthrax with Attenuated Recombinant Strains of Bacillus anthracis That Produce Protective Antigen
• Use of omentum flap for induction of free skin graft healing