Mutations in Catabolite Control Protein CcpA Separating Growth Effects from Catabolite Repression
AUTOR(ES)
Küster, Elke
FONTE
American Society for Microbiology
RESUMO
Carbon catabolite repression in Bacillus megaterium is mediated by the transcriptional regulator CcpA. A chromosomal deletion of ccpA eliminates catabolite repression and reduces the growth rate on glucose. We describe four single-amino-acid mutations in CcpA which separate the growth effect from catabolite repression, suggesting distinct regulatory pathways for these phenotypes.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=93908Documentos Relacionados
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