Mutagenic Effect of Temperature-Sensitive Mutants of Gene 42 (dCMP Hydroxymethylase) of Bacteriophage T4

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RESUMO

Certain temperature-sensitive mutants of gene 42 of bacteriophage T4 increase the reversion rates of some rII mutants in the same genome by about 4 to 10 times. This effect was usually found at 34 C, an intermediate permissive temperature, but not at 28 C.

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