Multi-species sequence comparison: the next frontier in genome annotation

AUTOR(ES)

Dubchak, Inna

FONTE

BioMed Central

RESUMO

Most current computational tools have been designed for pairwise comparisons of DNA sequences, and efficient extension of these tools to multiple species will require knowledge of the ideal evolutionary distance to choose and the development of new algorithms for alignment, analysis of conservation, and visualization of results.

Documentos Relacionados

• Identification and Characterization of Multi-Species Conserved Sequences
• Multi-species sequence comparison reveals dynamic evolution of the elastin gene that has involved purifying selection and lineage-specific insertions/deletions
• Orthologous gene-expression profiling in multi-species models: search for candidate genes
• WormBase: a multi-species resource for nematode biology and genomics
• Multi-species biofilm of Candida albicans and non-Candida albicans Candida species on acrylic substrate