Moxifloxacin Penetration in Bronchial Secretions of Mechanically Ventilated Patients with Pneumonia

AUTOR(ES)
FONTE

American Society for Microbiology

RESUMO

The pharmacokinetics of moxifloxacin was studied in 17 mechanically ventilated patients with pneumonia. Patients were given 400 mg of moxifloxacin intravenously. Blood samples and bronchial secretions were taken on days 1 and 4. A dose of 400 mg of moxifloxacin allows one to achieve efficient concentrations in bronchial secretions and plasma.

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