Mosaicism for trisomy 3q arising from an unbalanced, de novo t(3;15).

AUTOR(ES)

Stallings, R

RESUMO

We report on a 2 1/2 year old girl who is dysmorphic, developmentally delayed, and mosaic for an unbalanced, de novo translocation between chromosomes 3 and 15. The karyotype from peripheral blood lymphocytes is 46,XX (50) and the karyotype from skin fibroblasts is 46,XX (28)/46,XX,der(15)t(3;15)(q11;p11) (23). The mechanism for the generation of this unbalanced, de novo translocation is discussed.

Documentos Relacionados

• A case of partial trisomy 3q
• Trisomy 16q arising from a maternal 15p;16q translocation.
• Partial trisomy 3q causing mild Cornelia de Lange phenotype.
• Partial trisomy 3q and the mild Cornelia de Lange syndrome phenotype.
• De novo partial trisomy 15q (proximal type).