Morphometry of submucous and myenteric esophagic plexus of dogs experimentally reinfected with Trypanosoma cruzi
AUTOR(ES)
Machado, Evandro MM, Camilo Júnior, Deolino J, Pinheiro, Simone W, Lopes, Edison Reis, Fernandes, Alexandre J, Dias, João Carlos Pinto, Adad, Sheila J
FONTE
Memórias do Instituto Oswaldo Cruz
DATA DE PUBLICAÇÃO
2001-05
RESUMO
We carried out a morphometric study of the esophagus of cross-bred dogs experimentally infected or consecutively reinfected with Trypanosoma cruzi 147 and SC-1 strains, in order to verify denervation and/or neuronal hypertrophy in the intramural plexus. The animals were sacrificed in the chronic stage, 38 months after the initial infection. Neither nests of amastigotes, nor myositis or ganglionitis, were observed in all third inferior portions of esophageal rings analyzed. No nerve cell was identified in the submucous of this organ. There was no significant difference (p>0.05) between the number, maximum diameter, perimeter, or area and volume of the nerve cells of the myenteric plexus of infected and/or reinfected dogs and of the non-infected ones. In view of these results we may conclude that the 147 and SC-1 strains have little neurotropism and do not determine denervation and/or hypertrophy in the intramural esophageal plexuses in the animals studied, independent of the reinfections.
Documentos Relacionados
- Myenteric plexus is differentially affected by infection with distinct Trypanosoma cruzi strains in Beagle dogs
- Effect of acetylsalicylic acid on total myenteric neurons in mice experimentally infected with Trypanosoma cruzi
- Genitourinary changes in hamsters infected and reinfected with Trypanosoma cruzi
- Histological and histochemical observations on the myenteric and submucous plexuses of mammals.
- Vaccination of dogs with Trypanosoma rangeli induces antibodies against Trypanosoma cruzi in a rural area of Córdoba, Argentina