Morphological repercutions of burn injury components of the myenteric plexus in the jejunum of adults rats. / Repercussões morfológicas da lesão térmica corporal nos componentes do plexo mioentérico do jejuno de ratos adultos.

AUTOR(ES)
DATA DE PUBLICAÇÃO

2009

RESUMO

Burn is a determinant factor to alter body structures as the striated muscle. It also determines gastrintestinal mucosal atrophy what produce loss of selective barrier. With histochemical, immunohistochemical and light microscopy methods the myenteric plexus (MP) of the jejunum was evaluated in rats submitted to burn injury. The scalding was performed in 30% of the body surface. The MP and the mucosa of the oral (O), middle (M) and aboral (A) parts of the jejunum were analyzed four (q4) and ten (q10) days post-lesion. The loss of weight due the burn is not recovered in q10 where the jejunal surface area and the thickness of the mucosa decreased. The neuronal profile of nitregic neurons was similar in q4, q10. The density of nitregic neurons was lower in q10 showing that the time post injury is an important factor able to alter this parameter. The q4 and q10 groups exhibited neuronal bodies highly reactive to NADPH. The immunoreactivity to SP and VIP in q4 and q10 was expressed mainly in large varicosities.

ASSUNTO(S)

morfogênese animal mucosa intestinal jejunum animal anatomy lesões em animais burn injury lesão térmica corporal plexo mioentérico intestinal mucosa lesions in animals thermal body lesion intestino delgado animal morphogenesis jejuno de animal myenteric plexus anatomia small intestine

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