Mophologic and biochemical evaluation from articular disk of rat s TMJ submitted to low power laser therapy : experimental studies in bearer animals of tempromandibular joint disfunction / Avaliação morfologica e bioquimica do disco articular da ATM de ratos submetidos a terapia com laser de baixa potencia : estudo experimental em animais portadores de disfuncão temporomandibular

AUTOR(ES)
DATA DE PUBLICAÇÃO

2009

RESUMO

Disorders resulting from injury or disease related to TMJ affect the masticatory apparatus as a whole and are characterized as temporomandibular joint disorder (TMJD). It is known that about seven percent of world population requires treatment for the TMJD. Cartilaginous tissues, such as those that constitute the articular disc of the ATM, have a limited capacity for regeneration, and yet there are no reliable techniques and methods that encourage the growth of a new tissue, capable of assisting the treatment of trauma and degenerative diseases. Treatment with low power laser is one of the therapies used and, therefore, it is essential knowledge of their actions in terms of cellular and tissue. To this end, we used 24 male Lewis rats divided into four groups: GC control group GD animals in that group was given the botulinum toxin; GL group animals that received treatment with low-power laser; GDL animals in that group was given the botulinum toxin and then submitted to the low power laser therapy. Morphological analysis was performed by means of histological sections and stained by HE, and AT and picrosirius; biochemical analysis by electrophoresis in SDSpolyacrylamide gel and determination of proteins. It can be concluded based on morphological and biochemical results, the proposed model of TMD was shown satisfactory for studies of this disease, while treatment with the laser must submit their clinical protocols to a revaluation because it showed controversial results of point of tissue for promoting the synthesis of some components of the extracellular matrix and destruction of other essential for the proper functioning of the joint involved.

ASSUNTO(S)

temporomandibular joint disorders rat lasers rato - histologia rat lesão muscular lasers - uso terapeutico muscular danage rato - anatomia transtornos da articulação temporomandibular

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