Molecular detection of Mayaro virus during a dengue outbreak in the state of Mato Grosso, Central-West Brazil

AUTOR(ES)

Zuchi, Nayara, Heinen, Letícia Borges da Silva, Santos, Marcelo Adriano Mendes dos, Pereira, Fernanda Carla, Slhessarenko, Renata Dezengrini

FONTE

Mem. Inst. Oswaldo Cruz

DATA DE PUBLICAÇÃO

19/08/2014

RESUMO

Mayaro virus (MAYV) is frequently reported in Pan-Amazonia. The aim of this study was to investigate the circulation of alphaviruses during a dengue outbreak in the state of Mato Grosso, Brazil. Serum samples from dengue-suspected patients were subjected to multiplex semi-nested reverse transcriptase polymerase chain reaction for 11 flaviviruses and five alphaviruses, to nucleotide sequencing and to viral isolation. MAYV was detected in 15 (2.5%) of 604 patients. Twelve were co-infected with dengue virus 4, which was isolated from 10 patients. The molecular detection of MAYV in dengue-suspected patients suggests that other arboviruses may be silently circulating during dengue outbreaks in Brazil.

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