Modulation of nociceptive-like behavior in zebrafish (Danio rerio) by environmental stressors
AUTOR(ES)
Maximino, Caio
FONTE
Psychology & Neuroscience
DATA DE PUBLICAÇÃO
2011-06
RESUMO
Zebrafish have been demonstrated to react consistently to noxious chemical stimuli and present reliable phenotypes of stress, fear, and anxiety. In this article, we describe the modulation of nociceptive-like responses of zebrafish to fear-, stress-, and anxiety-eliciting situations. Animals were exposed to an alarm substance, confinement stress, or a novel environment before being injected with 1% acetic acid in the tail. The alarm substance and confinement stress reduced the display of erratic movements and tail-beating behavior elicited by acetic acid. The novelty of the environment, in contrast, increased the frequency of tail-beating behavior. The results suggest that descending modulatory control of nociception exists in zebrafish, with apparent fear- and stress-induced analgesia and anxiety-induced hyperalgesia.
Documentos Relacionados
- Production of Androgenetic Zebrafish (Danio Rerio)
- Ontogeny and nutritional control of adipogenesis in zebrafish (Danio rerio)
- Cytoskeletal and cellular adhesion proteins in zebrafish (Danio rerio) myogenesis
- Avaliação de padrões comportamentais induzidos por ansiolíticos em zebrafish (danio rerio)
- Zebrafish (Danio rerio) como modelo para estudo da toxicidade induzida pelo ferro