Model studies of interactions between nucleic acids and proteins: hydrogen bonding of amides with nucleic acid bases.
AUTOR(ES)
Lancelot, G
RESUMO
The formation of hydrogen bonded complexes between nucleic acid bases and acetamide has been studied by nuclear magnetic resonance in CDC13 at different temperatures. Pairs of hydrogen bonds are formed when acetamide binds to nucleic acid bases. Thermodynamic parameters have been computed and compared to those obtained for the association of carboxylic acids with nucleic acid bases. The role of hydrogen bonded complexes in the association of proteins with nucleic acids is discussed.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=327753Documentos Relacionados
- Theoretical calculations of base-base interactions in nucleic acids: I. Stacking interactions in free bases.
- Theoretical study on the proton chemical shifts of hydrogen bonded nucleic acid bases.
- Correlation of crystallographically determined and computationally predicted hydrogen-bonded pairing configurations of nucleic acid bases.
- A spectroscopic probe of stacking interactions between nucleic acid bases and tryptophan residues of proteins.
- Modification of interactions between neutrophils and staphylococci by lysosomotropic weak bases.
