Microbial transformations of 7,2-dimethylbenz[a]anthracene.
AUTOR(ES)
Wu, J
RESUMO
Microbial transformations of 7,12-dimethylbenz[a]anthracene, a carcinogenic polycyclic aromatic hydrocarbon, in cultures of Pseudomonas aeruginosa and Penicillium notatum were studied by high performance liquid chromatographic separation of metabolic fractions followed by gas chromatographic-mass spectrometric analysis of the metabolites. Two methyl-hydroxylated metabolites were identified in each of the incubations. The metabolic activation of the polycyclic aromatic hydrocarbon suggests a possible involvement of microorganisms in environmental carcinogenesis.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=243787Documentos Relacionados
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