Metabolism of 5-hydroxylysine in Pseudomonas fluorescens.
AUTOR(ES)
Friede, J D
RESUMO
Hydroxylysine is metabolized via two routes by a Pseudomonas fluorescens strain as shown by the oxidation of selected intermediates. Hydroxy-L-lysine is oxidized via a pathway analogous to the monooxygenase pathway for L-lysine, and data suggest that at least some of tthe enzymes are those involved in the metabolism of L-lysine. Hydroxy-L-lysine is also converted by a racemase to allohydroxy-D-lysine, which is then degraded via a pathway analogous to, but different from, that described for D-lysine, involving hydroxy-L-pipecolate, 2-amino-5-hydroxyadipate, and 2-hydroxyglutarate. Data obtained with mutants unable to oxidize L-pipecolate suggest that the enzymes for the metabolism of hydroxy-L-pipecolate are distinct from those for L-pipecolate. Studies on D- and L-lysine degradation have shown that the previously described pathways for these compounds are present in this soil pseudomonad.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=232916Documentos Relacionados
- Maltose metabolism of Pseudomonas fluorescens.
- Metabolism of volatile chlorinated aliphatic hydrocarbons by Pseudomonas fluorescens.
- Chromate resistance plasmid in Pseudomonas fluorescens.
- In vivo construction of a hybrid pathway for metabolism of 4-nitrotoluene in Pseudomonas fluorescens.
- Lysis of Trypanosoma cruzi by Pseudomonas fluorescens.