Meiotic recombination and chromosome segregation in Schizosaccharomyces pombe
AUTOR(ES)
Davis, Luther
FONTE
The National Academy of Sciences
RESUMO
In most organisms homologous recombination is vital for the proper segregation of chromosomes during meiosis, the formation of haploid sex cells from diploid precursors. This review compares meiotic recombination and chromosome segregation in the fission yeast Schizosaccharomyces pombe and the distantly related budding yeast Saccharomyces cerevisiae, two especially tractable microorganisms. Certain features, such as the occurrence of DNA breaks associated with recombination, appear similar, suggesting that these features may be common in eukaryotes. Other features, such as the role of these breaks and the ability of chromosomes to segregate faithfully in the absence of recombination, appear different, suggesting multiple solutions to the problems faced in meiosis.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=37449Documentos Relacionados
- The Role of Topoisomerase II in Meiotic Chromosome Condensation and Segregation in Schizosaccharomyces pombe
- Meiotic Recombination-Deficient Mutants of Schizosaccharomyces Pombe
- Cohesins are required for meiotic DNA breakage and recombination in Schizosaccharomyces pombe
- Dmc1 of Schizosaccharomyces pombe plays a role in meiotic recombination
- Seventeen Complementation Groups of Mutations Decreasing Meiotic Recombination in Schizosaccharomyces Pombe