Measurement of intestinal absorption of 57Co vitamin B12 by serum counting

AUTOR(ES)
RESUMO

The results of the measurement of vitamin B12 absorption by counting the radioactivity of 5 ml. serum obtained eight to 10 hours after the ingestion of an oral dose of 0·5 μg. vitamin B12 labelled with 0·5 μc. 57Co are compared with those obtained with the urinary excretion (Schilling) test. Inadequate urine collection and impaired renal function were responsible for low results in the Schilling test in four of the 12 control subjects, and an incomplete urine collection in four patients with pernicious anaemia could have led to doubt about the validity of the low result.

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