MCL-1–dependent leukemia cells are more sensitive to chemotherapy than BCL-2–dependent counterparts
AUTOR(ES)
Brunelle, Joslyn K.
FONTE
The Rockefeller University Press
RESUMO
Cancer-expressed anti-apoptotic protein BCL-2 is stable, whereas MCL-1 undergoes proteasome-dependent degradation in response to chemotherapeutic agents.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=2779245Documentos Relacionados
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