MAXAMIZE. A DNA sequencing strategy advisor.
AUTOR(ES)
Bach, R
RESUMO
The MAXAMIZE advisory system determines from user-provided restriction maps an optimal strategy to do nucleotide sequencing by methods involving end-labeled fragments. The maps may be either simple linear restriction maps of fragments or complex circular maps including restriction sites of a vector. The whole system is interactive and is written in the Genetic English language provided by the GENESIS System, a molecular genetics knowledge representation and manipulation package. In addition, MAXAMIZE provides bookkeeping facilities for sequencing and offers advise on how to verify the newly obtained sequence data.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=326134Documentos Relacionados
- A strategy of DNA sequencing employing computer programs.
- A Transposon-Based Strategy for Sequencing Repetitive DNA in Eukaryotic Genomes
- 'Long distance sequencer' method; a novel strategy for large DNA sequencing projects.
- Kilo-sequencing: an ordered strategy for rapid DNA sequence data acquisition.
- DNA sequence of the E. coli gyrB gene: application of a new sequencing strategy.