Maturation by LctT Is Required for Biosynthesis of Full-Length Lantibiotic Lacticin 481
AUTOR(ES)
Uguen, Patricia
FONTE
American Society for Microbiology
RESUMO
In lantibiotic lacticin 481 biosynthesis, LctT cleaves the precursor peptide and exports mature lantibiotic. Matrix-assisted laser desorption ionization-time of flight mass spectrometry revealed that a truncated form of lacticin 481 is produced in the absence of LctT or after cleavage site inactivation. Production of truncated lacticin 481 is 4-fold less efficient, and its specific activity is about 10-fold lower.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=544215Documentos Relacionados
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