Materiais para cimentação de restaurações protéticas: resposta no tecido subcutâneo de camundongos isogênicos e na polpa de dentes de cães / Luting materials for prosthetic restorations: Response in the subcutaneous tissue of isogenic mice and dogs pulp tissue

AUTOR(ES)
DATA DE PUBLICAÇÃO

2007

RESUMO

The purpose of this study was to evaluate the biocompatibility of different luting agents (Ketac Cem Easy Mix 3M ESPE and RelyX Unicem 3M ESPE), microscopically, by means of implants in the subcutaneous connective tissue of isogenic mice; microscopically and radiographically, after application to deep cavities, close to the pulp, in dogs teeth. In the study in subcutaneous connective tissue, 40 isogenic BALB/c mice were allocated in 9 groups with 3 experimental periods: Group I: Ketac Cem Easy Mix® (7 days), Group II: RelyX Unicem (7 days), Group III: empty polyethylene tube (7 days), Group IV: Ketac Cem Easy Mix (21 days) Group V: RelyX? Unicem (21 days), Group VI: empty polyethylene tube (21 days), Group VII: Ketac Cem Easy Mix (63 days), Group VIII: RelyX Unicem (63 days), Group IX: empty polyethylene tube (63 days). In the study in the pulp tissue of dogs teeth, 40 teeth (80 roots) of 4 dogs were used and assigned to 6 groups: Group I: Ketac Cem Easy Mix (7 days), Group II: RelyX Unicem (7 days), Group III: zinc oxide and eugenol cement (7 days), Group IV: Ketac Cem Easy Mix (70 days) Group V: RelyX Unicem (70 days), Group VI: zinc oxide and eugenol cement (70 days). The microscopic analysis of the subcutaneous connective tissue was performed under standard ligth microscopy, according to the following parameters: presence of inflammatory infiltrate (cellularity and cell type) and tissue repair. In the microscopic analysis in dogs teeth, a comprehensive description of dentin, pulp and periapical tissue characteristics was undertaken, based on the following aspects: presence of normal pulp; presence of reparative dentin; presence of ulceration; presence of pulpitis; and presence of pulp necrosis. The radiographic evaluation was performed by means of the analysis of periapical radiographs taken before the operative procedures and at the experimental periods, with respect to the integrity of the lamina dura, presence or absence of root resorptions and areas of periapical bone rarefaction. The results of the microscopic analysis demonstrated that, when applied to dentin, both cements did not cause adverse pulp reactions. Nevertheless, when applied directly to the pulp tissue, the luting agents triggered an intense inflammatory response, with pulp necrosis and development of periapical reaction. In the subcutaneous connective tissue of mice, Ketac Cem Easymix induced an inflammatory response and intense reactive phenomena at all analyzed periods. On the other hand, RelyX Unicem induced a discrete inflammatory response with tissue repair at the later periods. It may be concluded that RelyX Unicem and Ketac Cem Easymix luting agents presented satisfactory results when applied to the dentin of deep cavities without pulp exposure. However, when placed in contact with the subcutaneous connective tissue and pulp tissue in areas of micro-exposures, these materials presented unsatisfactory results.

ASSUNTO(S)

proteção pulpar indireta luting materials indirect pulp capping materiais para cimentação biocompatibility biocompatibilidade

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