Maridomycin, a New Macrolide Antibiotic: In Vivo Antibacterial Activity of 9-Propionylmaridomycin
AUTOR(ES)
Kondo, Masahiro
RESUMO
The in vivo protecting activity of 9-propionylmaridomycin, a derivative of the new macrolide antibiotic, maridomycin, was compared with that of other macrolide antibiotics in mice infected with Staphylococcus aureus, Streptococcus pyogenes, and Diplococcus pneumoniae. The protective effect was almost similar to that afforded by several known macrolide antibiotics in mice infected intraperitoneally with certain strains of the gram-positive species described above. The skin lesion caused by intradermal challenge of S. aureus in mice also responded very effectively to treatment with 9-propionylmaridomycin.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=444521Documentos Relacionados
- Maridomycin, a New Macrolide Antibiotic. In Vitro Antibacterial Activity of 9-Propionylmaridomycin
- Chemical Modification of Maridomycin, a New Macrolide Antibiotic
- Cefuroxime, a New Cephalosporin Antibiotic: Activity In Vivo
- In vitro antibacterial activity of faeriefungin, a new broad-spectrum polyene macrolide antibiotic.
- Cefuroxime, a New Cephalosporin Antibiotic: Activity In Vitro