Lymphocytotoxic antibodies in family members of patients with systemic lupus erythematosus.
AUTOR(ES)
DeHoratius, R J
RESUMO
57% of sera from 124 relatives of 28 patients with systemic lupus erythematosus (SLE) were found to have antibody directed against lymphocytes. The incidence in 60 members of 16 control families was 3%. Both consanguineous and nonconsanguineous relatives had the antibody in their sera. 68% of close household contacts of the SLE patients showed lymphocytotoxic antibody whereas only 23% of consanguineous relatives who had no household contact with the probands had this antibody. These data suggest that environmental factors may be important in the pathogenesis of SLE.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=301880Documentos Relacionados
- Brain-reactive lymphocytotoxic antibodies in the serum of patients with systemic lupus erythematosus.
- Serum lymphocytotoxic antibodies and neurocognitive function in systemic lupus erythematosus.
- Anticardiolipin antibodies in patients from Malaysia with systemic lupus erythematosus.
- Tuberculosis in patients with systemic lupus erythematosus.
- Antitissue antibodies in monozygotic twins with systemic lupus erythematosus.
