Lupus anticoagulants in systemic lupus erythematosus: prevalence and clinical associations.
AUTOR(ES)
Padmakumar, K
RESUMO
The prevalence of lupus anticoagulant (LAC) and its relation with reported clinical associations has been determined in 55 patients with systemic lupus erythematosus (SLE) from northern India who were studied prospectively. Kaolin clotting time was used to screen for LAC, which was detected in seven (13%) of the patients. Significant associations were found between LAC and thrombotic events, onset of disease at an early age, and disease of shorter duration. No statistically significant association could be found between LAC and recurrent abortions, pulmonary hypertension, thrombocytopenia, and neurological manifestations. It is concluded that LAC is a useful marker for a subset of patients with SLE at risk of thromboembolic events.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1004293Documentos Relacionados
- Antibodies to histones in systemic lupus erythematosus: prevalence, specificity, and relationship to clinical and laboratory features.
- Jaccoud arthropathy in systemic lupus erythematosus: clinical and serological findings
- Investigation of the prevalence and clinical associations of antibodies to human fibronectin in systemic lupus erythematosus.
- Coexistent rheumatoid arthritis and systemic lupus erythematosus: clinical, serological, and phenotypic features.
- Muscle biopsy abnormalities in systemic lupus erythematosus: correlation with clinical and laboratory parameters.
