Low predictive value of polymerase chain reaction for diagnosis of cytomegalovirus disease in liver transplant recipients.
AUTOR(ES)
Delgado, R
RESUMO
The polymerase chain reaction (PCR) and viral culture techniques were prospectively compared for the detection of cytomegalovirus (CMV) in blood samples from 24 liver transplant recipients. Nine patients had one or more episodes of viremia, seven of which were clinically symptomatic infections. All samples in which CMV was isolated by culture were positive by the PCR. However, the PCR result was also positive for one or more samples from 11 patients who never developed CMV-related symptoms. Although the PCR is a very sensitive technique for CMV detection in blood samples from liver transplant recipients, it is not useful as a marker of symptomatic CMV disease.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=265398Documentos Relacionados
- Qualitative and semiquantitative polymerase chain reaction testing for cytomegalovirus DNA in serum allows prediction of CMV related disease in liver transplant recipients.
- Diagnosis of cytomegalovirus infection in heart transplant recipients.
- Detection of cytomegalovirus DNA in sera of liver transplant recipients.
- Risk of liver disease in HCV-seropositive kidney transplant recipients.
- Diagnosis of toxoplasma infection in cardiac transplant recipients using the polymerase chain reaction.
