Levels of Ligand receptor activator nuclear factor kb (RANKL) and Osteoprotegerin (OPG) in fluid peri-implant crevicular implants charged immediately in patients with osteopenia / Níveis do ligante receptor ativador do fator nuclear kb (Rankl) e osteoprotegerina (OPG) no fluido crevicular peri-implantar de implantes carregados imediatamente em pacientes com osteopenia

AUTOR(ES)
DATA DE PUBLICAÇÃO

2011

RESUMO

The successful outcome of immediately loaded implants is influenced by a number of confounding factors, such as bone remodeling response and bone quality in the periimplant site. Bone resorption is controlled by the interaction of the receptor activator of the NF-kß ligand (RANKL) and osteoprotegerin (OPG). RANKL induces osteoclast formation and activation for binding on the receptor activator of the NF-kß (RANK), while OPG is a decoy receptor for RANKL that inhibits osteoclastogenesis. The aim of this prospective-controlled study was to evaluate the osteoclastogenesisrelated factors (RANKL and OPG) levels in the peri-implant crevicular fluid (PICF) of immediately loaded implants in patients with and without osteopenia after 120 days of loading. Twenty-three patients were divided according to criteria established by the World Health Organization: control (n=10 patients; T-score -1) and osteopenia (n=13 patients; -10.05), although there were significant differences between baseline and 120 days post-surgery PICF levels (p<0.001). Within the limits of this study, it could be suggested that osteopenia did not influenced the peri-implant tissue response around immediately loaded implants, after 120 days post-surgery.

ASSUNTO(S)

immediate loading dental implants opg rankl osteoporose osteopenia carga imediata implante dental odontologia osteopenia osteoporosis rankl opg

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